HPLC + MS
Independently tested for identity and purity
NP-RETA50-02
Aug 28, 2026
99.93%
View Certificate of Analysis
CAS# 2381089-83-2
Also Known As LY3437943
Length 39 AA
Target GLP-1R / GIPR / GcgR
Form Lyophilized Powder
Molecular Weight
Chain Length
Compound Class
Retatrutide (LY3437943, CAS# 2381089-83-2) is a synthetic 39-amino-acid peptide classified as a triple receptor agonist, with binding activity at the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GcgR). It is studied in vitro as a pharmacological tool for investigating simultaneous multi-receptor agonism across the incretin signalling system. Supplied by NexPept as a lyophilized powder for in vitro laboratory research use.
Molecular Profile
CAS#, molecular weight, chain length, analytical data
CAS#, molecular weight, chain length, analytical data
| Property | Value |
|---|---|
| CAS Number | 2381089-83-2 |
| Research Designation | LY3437943 |
| Molecular Weight | ~4731.33 g/mol |
| Chain Length | 39 amino acids |
| Compound Class | Synthetic incretin-based peptide — triple receptor agonist |
| Receptor Targets | GLP-1R, GIPR, GcgR |
| Physical Form | Lyophilized powder |
| Analytical Method | High-Performance Liquid Chromatography (HPLC) + Mass Spectrometry (MS) |
| Appearance | White to off-white lyophilized solid |
In Vitro Research Context
Receptor pharmacology — laboratory use only
Receptor pharmacology — laboratory use only
Glucagon-like peptide-1 receptor — a component of the incretin signalling pathway studied in receptor pharmacology.
Glucose-dependent insulinotropic polypeptide receptor — investigated in incretin-related signalling research.
Glucagon receptor — studied in hepatic and metabolic signalling research contexts.
Retatrutide is used in preclinical in vitro settings as a pharmacological tool for investigating simultaneous multi-receptor agonism across the incretin signalling system. Research applications include receptor binding assays, competitive displacement studies, and in vitro signalling cascade analysis by qualified research personnel in controlled laboratory environments.
Research context: Retatrutide is an investigational compound studied in scientific research involving GLP-1R, GIPR, and GcgR signalling pathways. Research into this compound remains ongoing. It has not been authorized by Health Canada for human or veterinary use.
Available Formats
10mg · 20mg · 50mg — lyophilized powder
10mg · 20mg · 50mg — lyophilized powder
| Format | Net Quantity | Physical Form |
|---|---|---|
| Retatrutide 10mg | 10 mg / vial | Lyophilized powder |
| Retatrutide 20mg | 20 mg / vial | Lyophilized powder |
| Retatrutide 50mg | 50 mg / vial | Lyophilized powder |
All formats are sourced from the same verified batch. Quantity for use should be determined based on your specific in vitro research protocol by qualified research personnel.
Laboratory Storage
Controlled storage conditions for lyophilized material
Controlled storage conditions for lyophilized material
Store sealed lyophilized material under controlled laboratory conditions in accordance with validated institutional SOPs and applicable technical documentation. Protect from moisture and light. Handling conditions should be established by qualified research personnel in accordance with the specific experimental protocol.
Note: No preparation, reconstitution, or administration instructions are provided. This compound is supplied for in vitro laboratory research use only. All handling must be conducted by qualified personnel following institutional safety protocols.
Research Literature
Scientific references & related resources
Scientific references & related resources
PubMed — LY3437943 / Retatrutide — peer-reviewed scientific literature on this compound
Retatrutide Canada — NexPept compound overview and in vitro research context
Research Peptides in Canada — sourcing and research context for Canadian laboratories
What Are Research Peptides? — compound classification and in vitro research context
This product is supplied exclusively for in vitro laboratory and non-clinical research use by qualified research personnel. It is not authorized by Health Canada for human or veterinary use. No therapeutic, clinical, or health claims are made.
This material must not be administered to humans or animals. No dosage, preparation, reconstitution, or administration instructions are provided or implied. All handling and use must be conducted by qualified personnel in accordance with applicable institutional policies and legal requirements.
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